Transglutaminase 5 antibody (C-Term)

Catalog No. ABIN1887288

Product Details anti-Transglutaminase 5 Antibody

Target: Transglutaminase 5 (TGM5)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transglutaminase 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): TGM5 antibody is predicted to not cross-react with other TGase protein family members. Multiple isoforms of TGM5 are known to exist.

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the carboxy terminus of human TGM5.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for Transglutaminase 5

Target: Transglutaminase 5 (TGM5)

Alternative Name: TGM5 (TGM5 Products)

Synonyms: TGM5 antibody, TGASE5 antibody, TGASEX antibody, TGMX antibody, TGX antibody, 2310007C07Rik antibody, TGx antibody, transglutaminase 5 antibody, TGM5 antibody, tgm5 antibody, Tgm5 antibody

Background: Transglutaminases (TGM) are a family of structurally and functionally related Ca2+-dependent enzymes (TGases) that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks.TGases influence numerous biological processes, including blood coagulation, cell differentiation, fertilization and apoptosis.TGM5 belongs to the transglutaminase superfamily and catalyzes the cross-linking of proteins between glutamine and lysine residues, often resulting in stabilization of protein assemblies.TGM5 is also expressed in the human hair follicle.Defects in TGM5 are associated with acral peeling skin syndrome.
Synonyms: Transglutaminase 5, protein-glutamine gamma-glutamyltransferase 5, TGase-5, TGase X, TGMX, TGX

NCBI Accession: NP_963925