VASH1 antibody (C-Term)

Catalog No. ABIN1887291

Product Details anti-VASH1 Antibody

Target: VASH1 (Vasohibin 1 (VASH1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VASH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): VASH1 antibody is predicted to not cross-react with other vasohibin protein family members. At least two isoforms are known to exist, this antibody will recognize only the long isoform.

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the carboxy terminus of human VASH1.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for VASH1

Target: VASH1 (Vasohibin 1 (VASH1))

Alternative Name: VASH1 (VASH1 Products)

Synonyms: KIAA1036 antibody, AI834978 antibody, D930046M13Rik antibody, G630009D10Rik antibody, RGD1564082 antibody, vasohibin 1 antibody, VASH1 antibody, vash1 antibody, Vash1 antibody

Background: VASH1 was originally identified as an endothelium-derived vascular endothelial growth factor (VEGF)-inducible angiogenesis inhibitor that acts in a negative feedback manner.VASH1 mRNA is expressed brain, heart, kidney and placenta in the adult, with robust expression in various organs during embryonic development.VASH1 expression in tumor cells and tumor vasculature is silenced by methylation by increased expression of Zeste homolog 2 (EZH2).The increase of EZH2 expression is induced by VEGF stimulation, leading to poor clinical prognosis.Recombinant adenovirus expressing VASH prevented tumor angiogenesis and inhibited tumor growth, suggesting that it may be a potentially valuable antitumor therapy in the clinic.
Synonyms: Vasohibin1

NCBI Accession: NP_055724