TNFSF13B
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice
Avoid freezing and thawing repeatly.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Target
BAFF (TNFSF13B)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
Members in the TNF superfamily regulate immune responses and induce apoptosis.A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF-kappaB and c-jun N-terminal Kinase).BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion.Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R.BAFF and its receptors are essential for B cell development, survival, and humoral immune responses.BAFF is involved in the development of autoimmune diseases including systemic lupus erythaematosus and rheumatoid arthritis. Synonyms: BLyS, Thank, Tall