LY9 antibody (C-Term)

Catalog No. ABIN1887433

Product Details anti-LY9 Antibody

Target: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LY9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): At least three isoforms of SLAMF3 are known to exist. SLAMF3 antibody is predicted to not cross-react with other SLAM protein family members.

Purification: Affinity chromatography purified via peptide column

Immunogen: SLAMF3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human SLAMF3.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for LY9

Target: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Alternative Name: SLAMF3 (CD229 Products)

Synonyms: LY9 antibody, CD229 antibody, SLAMF3 antibody, hly9 antibody, mLY9 antibody, AI893573 antibody, Lgp100 antibody, Ly-9 antibody, T100 antibody, lymphocyte antigen 9 antibody, LY9 antibody, Ly9 antibody

Background: The signaling lymphocyte-activation molecule family member 3 (SLAMF3), also known as LY9, is a cell surface receptor that is expressed on T and B lymphocytes and belongs to the CD150/SLAMF1 receptor family.SLAMF3 was identified through a yeast two-hybrid screening in which SLAMF3 bound to the X-linked lymphoproliferative disease gene product SAP, suggesting that in activated T cells, SLAMF3 signaling can be triggered SAP.Its expression on the cell surface appears to be regulated via its interaction with the clathrin-associated adaptor complex 2 (AP-2).Despite its similarity to SLAMF1 in structure and interactions with SAP, SLAMF3-deficient mice do not exhibit phenotypic characteristics associated with SLAMF1- and SAP-deficient mice, suggesting that SLAMF3 plays other roles in T cell activation.
Synonyms: Signaling lymphocytic activation molecule family member 3, lymphocyte antigen 9, LY9, hly9, CD229

NCBI Accession: NP_1769

Pathways: BCR Signaling