TGM7 antibody is predicted to not cross-react with other TGase protein family members. At least two isoforms of TGM7 are known to exist, this antibody will recognize both isoforms.
Purification
Affinity chromatography purified via peptide column
Immunogen
13 amino acid peptide near the center of human TGM7.
TGM7
Reactivity: Human
WB
Host: Sheep
Polyclonal
Biotin
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice
Avoid freezing and thawing repeatly.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Transglutaminases (TGM) are a family of structurally and functionally related Ca2+-dependent enzymes (TGases) that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks.TGases influence numerous biological processes, including blood coagulation, cell differentiation, fertilization and apoptosis.TGM7 belongs to the transglutaminase superfamily and is also thought to catalyze the cross-linking of proteins, often resulting in stabilization of protein assemblies.Little is known of the role of TGM7, but defects in the highly related protein TGM5 are associated with acral peeling skin syndrome. Synonyms: Transglutaminase 7, protein-glutamine gamma-glutamyltransferase 7, TGase-7, TGase Z, TGMZ