C1QTNF2 antibody (Center)

Catalog No. ABIN1887585

Product Details anti-C1QTNF2 Antibody

Target: C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QTNF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide from near the center of human CTRP2.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for C1QTNF2

Target: C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

Alternative Name: CTRP2 (C1QTNF2 Products)

Synonyms: C1QTNF2 antibody, fe50b04 antibody, wu:fe50b04 antibody, CTRP2 antibody, zacrp2 antibody, 1810033K05Rik antibody, Ctrp2 antibody, RGD1561041 antibody, C1q and tumor necrosis factor related protein 2 antibody, C1q and TNF related 2 antibody, C1QTNF2 antibody, c1qtnf2 antibody, C1qtnf2 antibody

Background: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines.One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7.Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues.These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism.An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene.Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin.Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation.

NCBI Accession: NP_114114