DAPK3 antibody (Center)

Catalog No. ABIN1887768

Product Details anti-DAPK3 Antibody

Target: DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAPK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids near the center of human ZIP kinase.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for DAPK3

Target: DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))

Alternative Name: ZIPK (DAPK3 Products)

Synonyms: DAPK3 antibody, dapk3 antibody, wu:fc25b08 antibody, si:dkey-57k2.5 antibody, MGC114871 antibody, ZIP antibody, ZIPK antibody, dlk antibody, Dapkl antibody, death associated protein kinase 3 antibody, death-associated protein kinase 3 antibody, death-associated protein kinase 3 L homeolog antibody, DAPK3 antibody, dapk3 antibody, dapk3.L antibody, Dapk3 antibody

Background: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases.Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis.A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase.ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family.ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon.Overexpression of ZIP kinase induces apoptosis.ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities.The messenger RNA was ubiquitously expressed in various tissues.
Synonyms: ZIPK

Molecular Weight: 40 kDa