CX3CR1 antibody (Extracellular Loop)

Catalog No. ABIN1887799

Product Details anti-CX3CR1 Antibody

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Binding Specificity: Extracellular Loop

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CX3CR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids in a extracellular loop of human CX3CR1.The sequence is identical to that of rat CX3CR1 and differs from that of mouse CX3CR1 by one amino acid.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Alternative Name: CX3CR1 (CX3CR1 Products)

Synonyms: CCRL1 antibody, CMKBRL1 antibody, CMKDR1 antibody, GPR13 antibody, GPRV28 antibody, V28 antibody, Rbs11 antibody, C-X3-C motif chemokine receptor 1 antibody, chemokine (C-X3-C motif) receptor 1 antibody, CX3C chemokine receptor 1 antibody, CX3CR1 antibody, Cx3cr1 antibody, LOC100559882 antibody

Background: CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection.The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively.The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1.Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine.CX3CR1 mediates leukocyte migration and adhesion.CX3CR1 is expressed in a variety of human tissues and cell lines.
Synonyms: V28

Molecular Weight: 50 kDa

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin