STEAP3 antibody (N-Term)

Catalog No. ABIN1887914

Product Details anti-STEAP3 Antibody

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): This STEAP3 antibody does not cross-react with other STEAP proteins.

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide from near the amino terminus of human STEAP3.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for STEAP3

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Alternative Name: STEAP3 (STEAP3 Products)

Synonyms: STEAP3 antibody, 1010001D01Rik antibody, Tsap6 antibody, pHyde antibody, AHMIO2 antibody, STMP3 antibody, TSAP6 antibody, dudlin-2 antibody, STEAP3 metalloreductase antibody, STEAP family member 3 antibody, STEAP3 antibody, steap3 antibody, Steap3 antibody

Background: The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue.Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction.STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome.Overexpression of STEAP3 stimulates iron reduction, mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
Synonyms: Six transmembrane epithelial antigen of prostate 3, dudulin-2

Pathways: Transition Metal Ion Homeostasis