RIMS3 antibody (N-Term)

Catalog No. ABIN1888035

Product Details anti-RIMS3 Antibody

Target: RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIMS3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): This antibody is predicted to have no cross-reactivity to other Rim proteins.

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide from near the amino terminus of human Rim3.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for RIMS3

Target: RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))

Alternative Name: Rim3 (RIMS3 Products)

Synonyms: NIM3 antibody, RIM3 antibody, Nim2 antibody, Nim3 antibody, A730060M23Rik antibody, Rim3 antibody, mKIAA0237 antibody, RIMS3 antibody, MGC145981 antibody, si:ch211-239d6.1 antibody, regulating synaptic membrane exocytosis 3 antibody, RIMS3 antibody, Rims3 antibody, rims3 antibody

Background: Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity.While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3.Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis.Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.
Synonyms: Rab3-interacting molecule 3, regulating synaptic membrane exocytosis 3, RIM3 gamma, RIMS3, NIM3

NCBI Accession: NP_055562

Pathways: Stem Cell Maintenance, Synaptic Vesicle Exocytosis