CCDC134 antibody (N-Term)

Catalog No. ABIN1888042

Product Details anti-CCDC134 Antibody

Target: CCDC134 (Coiled-Coil Domain Containing 134 (CCDC134))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC134 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the amino terminus of human CCDC134.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for CCDC134

Target: CCDC134 (Coiled-Coil Domain Containing 134 (CCDC134))

Alternative Name: CCDC134 (CCDC134 Products)

Synonyms: dJ821D11.3 antibody, 2310042L06Rik antibody, AW208859 antibody, si:dkey-167k11.5 antibody, coiled-coil domain containing 134 antibody, si:dkey-167k11.5 antibody, CCDC134 antibody, Ccdc134 antibody

Background: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments.One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein.Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription.CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.
Synonyms: CCDC134, Coiled-coil domain containing 134

NCBI Accession: NP_079097