CCDC141 antibody (N-Term)

Catalog No. ABIN1888153

Product Details anti-CCDC141 Antibody

Target: CCDC141 (Coiled-Coil Domain Containing 141 (CCDC141))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC141 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: At least four isoforms of CCDC141 are known to exist.

Purification: Affinity chromatography purified via peptide column

Immunogen: CCDC141 antibody was raised against an 18 amino acid peptide near the amino terminus of human CCDC141.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for CCDC141

Target: CCDC141 (Coiled-Coil Domain Containing 141 (CCDC141))

Alternative Name: CCDC141 (CCDC141 Products)

Synonyms: CAMDI antibody, 2610301F02Rik antibody, ENSMUSG00000075261 antibody, coiled-coil domain containing 141 antibody, CCDC141 antibody, Ccdc141 antibody

Background: Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II.CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner.Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development.
Synonyms: Coiled-coil domain-containing protein 141, CAMDI

NCBI Accession: NP_775919