STK17A antibody (N-Term)

Catalog No. ABIN1888195

Product Details anti-STK17A Antibody

Target: STK17A (serine/threonine Kinase 17a (STK17A))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK17A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Cross-Reactivity (Details): No cross responses to DRAK2, DAP or ZIP kinases.

Purification: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids near the amino terminus of human DRAK1.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for STK17A

Target: STK17A (serine/threonine Kinase 17a (STK17A))

Alternative Name: DRAK1 (STK17A Products)

Synonyms: STK17A antibody, DRAK1 antibody, RDRAK1 antibody, serine/threonine kinase 17a antibody, serine/threonine kinase 17a L homeolog antibody, STK17A antibody, stk17a antibody, stk17a.L antibody

Background: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases.Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis.Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases.DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain.Overexpression of DRAK1 induces apoptosis.DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities.DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

Molecular Weight: 50 kDa

UniProt: Q9UEE5