Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (Tyr 641) antibody

Details for Product No. ABIN197185
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Antigen
Synonyms D12S1644, IL-4-STAT, STAT6B, STAT6C
Epitope
Tyr 641
(45), (33), (19), (12), (7), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(238), (99), (90), (15), (12), (8), (4)
Host
Rabbit
(201), (49), (3), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1)
Application
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(187), (81), (76), (52), (39), (30), (19), (15), (14), (6), (5), (1)
Pubmed 5 references available
Quantity 50 µg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN197185
253.00 $
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human STAT6 around the phosphorylation site of tyrosine 641 (R-G-YP-V-P).
Specificity STAT6 antibody detects endogenous levels of total STAT6 protein.
Purification Affinity-chromatography using epitope-specific immunogen
Alternative Name STAT6
Background Alternate names: IL-4 Stat, Signal transducer and activator of transcription 6
Gene ID 6778
NCBI Accession NP_001171549
UniProt P42226
Research Area Chromatin and Nuclear Signaling, Signaling, Receptors, Inflammation
Application Notes Western Blot: 1: 500~1: 1000. Immunohistochemistry: 1: 50~1: 100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS(without Mg2+ and Ca2+), pH 7.4 containing 150mM NaCl, 0.02% sodium azide and 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Expiry Date 12 months
Supplier Images
anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (Tyr 641) antibody anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (Tyr 641) antibody
anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (Tyr 641) antibody (2) anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (Tyr 641) antibody (Image 2)
Background publications Quelle, Shimoda, Thierfelder et al.: "Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis." in: Molecular and cellular biology, Vol. 15, Issue 6, pp. 3336-43, 1995 (PubMed).

Hou, Schindler, Henzel et al.: "An interleukin-4-induced transcription factor: IL-4 Stat." in: Science (New York, N.Y.), Vol. 265, Issue 5179, pp. 1701-6, 1994 (PubMed).

Takeda, Tanaka, Shi et al.: "Essential role of Stat6 in IL-4 signalling." in: Nature, Vol. 380, Issue 6575, pp. 627-30, 1996 (PubMed).

Malabarba, Rui, Deutsch et al.: "Interleukin-13 is a potent activator of JAK3 and STAT6 in cells expressing interleukin-2 receptor-gamma and interleukin-4 receptor-alpha." in: The Biochemical journal, Vol. 319 ( Pt 3), pp. 865-72, 1996 (PubMed).

Nelms, Keegan, Zamorano et al.: "The IL-4 receptor: signaling mechanisms and biologic functions." in: Annual review of immunology, Vol. 17, pp. 701-38, 1999 (PubMed).

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