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CD300E antibody

CD300E Reactivity: Human WB, FACS, IP Host: Mouse Monoclonal UP-H2 unconjugated
Catalog No. ABIN1981868
  • Target See all CD300E Antibodies
    CD300E (CD300e Molecule (CD300E))
    Reactivity
    • 34
    • 8
    Human
    Host
    • 22
    • 12
    Mouse
    Clonality
    • 23
    • 11
    Monoclonal
    Conjugate
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD300E antibody is un-conjugated
    Application
    • 19
    • 14
    • 11
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
    Specificity
    The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    CD300e-HA-transfected cells
    Clone
    UP-H2
    Isotype
    IgG1 kappa
  • Application Notes
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze. Do not use after expiration date stamped on vial label.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Brckalo, Calzetti, Pérez-Cabezas, Borrs, Cassatella, López-Botet: "Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells." in: European journal of immunology, Vol. 40, Issue 3, pp. 722-32, (2010) (PubMed).

  • Target
    CD300E (CD300e Molecule (CD300E))
    Alternative Name
    CD300e (CD300E Products)
    Synonyms
    BC034097 antibody, CLM2 antibody, Cd300le antibody, TREM5 antibody, CD300LE antibody, CLM-2 antibody, CMRF35-A5 antibody, IREM-2 antibody, IREM2 antibody, PIgR-2 antibody, PIgR2 antibody, CD300E molecule antibody, CD300e molecule antibody, Cd300e antibody, CD300E antibody
    Background
    CD300e molecule,CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.,CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2
    Gene ID
    342510
    UniProt
    Q496F6
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