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LRRC32 antibody

LRRC32 Reactivity: Human WB Host: Mouse Monoclonal GARP5 unconjugated
Catalog No. ABIN1981876
  • Target See all LRRC32 Antibodies
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Reactivity
    • 26
    • 10
    • 9
    • 1
    Human
    Host
    • 20
    • 12
    • 1
    • 1
    Mouse
    Clonality
    • 21
    • 13
    Monoclonal
    Conjugate
    • 18
    • 7
    • 4
    • 2
    • 2
    • 1
    This LRRC32 antibody is un-conjugated
    Application
    • 17
    • 15
    • 14
    • 6
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Specificity
    The mouse monoclonal antibody GARP5 recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    Purified human sGARP protein
    Clone
    GARP5
    Isotype
    IgG1
    Top Product
    Discover our top product LRRC32 Primary Antibody
  • Application Notes
    Western blotting: Recommended dilution: 1-2 μg/mL, positive control: human thrombocytes, reducing conditions
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze. Do not use after expiration date stamped on vial label.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Wang, Zhu, Dong, Shi, Lu, Springer: "GARP regulates the bioavailability and activation of TGF?." in: Molecular biology of the cell, Vol. 23, Issue 6, pp. 1129-39, (2012) (PubMed).

  • Target
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Alternative Name
    GARP / LRRC32 (LRRC32 Products)
    Synonyms
    D11S833E antibody, GARP antibody, AI426318 antibody, D11S833Eh antibody, D7H11S833E antibody, EG434215 antibody, Garp antibody, leucine rich repeat containing 32 antibody, LRRC32 antibody, Lrrc32 antibody
    Background
    Leucine rich repeat containing 32,GARP (glycoprotein A repetitions predominant protein), also known as garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.,GARP, D11S833E
    Gene ID
    2615
    UniProt
    Q14392
    Pathways
    Activated T Cell Proliferation
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