PAPPA antibody (AA 95-302) (Biotin)

Catalog No. ABIN1993437

Product Details anti-PAPPA Antibody (Biotin)

Target: PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))

Binding Specificity: AA 95-302

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPPA antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Pappalysin-1 protein (95-302AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PAPPA

Target: PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))

Alternative Name: PAPPA (PAPPA Products)

Synonyms: 8430414N03Rik antibody, IGFBP-4ase antibody, PAG1 antibody, PAPP-A antibody, ASBABP2 antibody, DIPLA1 antibody, PAPA antibody, PAPPA1 antibody, Pappa antibody, pappalysin 1 antibody, pregnancy-associated plasma protein A antibody, PAPPA antibody, Pappa antibody, Pappa1 antibody

Background:

Background: Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.

Aliases: ASBABP2 antibody, Aspecific BCL2 ARE binding protein 2 antibody, Differentially placenta 1 expressed protein antibody, DIPLA1 antibody, EC 3.4.24.79 antibody, IGF dependent IGFBP 4 protease antibody, IGF-dependent IGFBP-4 protease antibody, IGFBP 4ase antibody, IGFBP-4ase antibody, IGFBP4ase antibody, Insulin like growth factor dependent IGF binding protein 4 protease antibody, Insulin-like growth factor-dependent IGF-binding protein 4 protease antibody, PAPA antibody, PAPP A antibody, PAPP-A antibody, PAPP1_HUMAN antibody, PAPPA antibody, PAPPA1 antibody, Pappalysin 1 precursor antibody, Pappalysin-1 antibody, Pregnancy Associated Plasma Protein A antibody, Pregnancy associated plasma protein A pappalysin 1 antibody, Pregnancy-associated plasma protein A antibody

UniProt: Q13219