JNK antibody

Catalog No. ABIN199352

The Mouse Monoclonal anti-JNK antibody is suitable to detect JNK in samples from Human. It has been validated for WB and IF.

Quick Overview for JNK antibody (ABIN199352)

Target: JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This JNK antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-JNK Antibody

Specificity: Reacts with JNK1 in both transfected and endogenous cell lines on Western blots. This antibody may cross-react with JNK3 in an overexpressed cell lysate, but the cross reactivity to JNK2 has not been observed. This antibody identifies a 54kD band on Western blot analysis. Reactivity is confirmed with A431 cell lysates.

Purification: Protein A Column

Immunogen: Recombinant GST-fusion protein of JNK1.

Isotype: IgG1

Application Details

Application Notes: IF (5 - 10 µg/mL), WB (1 - 3 µg/mL)

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4, 0.1% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Long term: Add glycerol (40-50%) -20°C, Short term: +4°C

Target Details for JNK

Target: JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

Alternative Name: MAPK8 / JNK1 / JNK

Background: Standard Gene Symbol: MAPK8, Gene Family: Protein Kinase, Gene Subfamily: MAPK, Synonyms: MAPK8, JNK, JNK1, JNK1A2, JNK-46, MAP kinase 8, PRKM8, SAPK1, SAPK1c, MAPK 8, C-Jun N-terminal kinase 1, JNK21B1/2, JUN N-terminal kinase

Gene ID: 5599

UniProt: P45983

Pathways: MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins