PSMB4 antibody (AA 46-264) (HRP)

Catalog No. ABIN1993692

Product Details anti-PSMB4 Antibody (HRP)

Target: PSMB4 (Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4))

Binding Specificity: AA 46-264

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMB4 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Proteasome subunit beta type-4 protein (46-264AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PSMB4

Target: PSMB4 (Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4))

Alternative Name: PSMB4 (PSMB4 Products)

Synonyms: An18g06680 antibody, PSMB4 antibody, Pros-27 antibody, HN3 antibody, HsN3 antibody, PROS-26 antibody, PROS26 antibody, im:6909492 antibody, zgc:110330 antibody, proteasome subunit beta type-4 antibody, proteasome subunit beta 4 antibody, proteasome (prosome, macropain) subunit, beta type 4 antibody, proteasome subunit beta 4 L homeolog antibody, ANI_1_890164 antibody, PSMB4 antibody, psmb4 antibody, Psmb4 antibody, psmb4.L antibody

Background:

Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal macrophage proteasome. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.

Aliases: 26 kDa prosomal protein antibody, HN3 antibody, HsBPROS26 antibody, HSN3 antibody, Macropain beta chain antibody, Multicatalytic endopeptidase complex beta chain antibody, PROS-26 antibody, PROS26 antibody, Proteasome (prosome macropain) subunit beta type 4 antibody, Proteasome beta 4 subunit antibody, Proteasome beta chain antibody, Proteasome chain 3 antibody, Proteasome subunit beta 4 antibody, Proteasome subunit beta type 4 antibody, Proteasome subunit beta type-4 antibody, Proteasome subunit HsN3 antibody, PSB4_HUMAN antibody, PSMB 4 antibody, PSMB4 antibody

UniProt: P28070

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA