TSH receptor antibody (AA 21-413) (HRP)

Catalog No. ABIN1994307

Product Details anti-TSH receptor Antibody (HRP)

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Binding Specificity: AA 21-413

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSH receptor antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Thyrotropin receptor protein (21-413AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Alternative Name: TSHR (TSHR Products)

Synonyms: CHNG1 antibody, LGR3 antibody, hTSHR-I antibody, AI481368 antibody, hypothroid antibody, hyt antibody, pet antibody, TSHRA antibody, TSH-R antibody, thyroid stimulating hormone receptor antibody, tshr antibody, TSHR antibody, Tshr antibody

Background:

Background: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099). Plays a central role in controlling thyroid cell metabolism (By similarity).

Aliases: CHNG1 antibody, hTSHR I antibody, hTSHRI antibody, LGR 3 antibody, LGR3 antibody, MGC75129 antibody, Seven transmembrane helix receptor antibody, Thyroid adenoma hyperfunctioning antibody, Thyroid carcinoma with thyrotoxicosis antibody, Thyroid stimulating hormone receptor antibody, Thyroid stimulating hormone receptor, isoform 2 antibody, Thyroid-stimulating hormone receptor antibody, Thyrotropin receptor antibody, Thyrotropin receptor I antibody, Thyrotropin receptor I, hTSHR I antibody, TSH R antibody, TSH Receptor antibody, TSH-R antibody, TSHR antibody, TSHR_HUMAN antibody

UniProt: P16473

Pathways: Thyroid Hormone Synthesis