KIT antibody

Catalog No. ABIN212879

The Rat Monoclonal anti-KIT antibody is suitable to detect KIT in samples from Mouse. It has been validated for FACS, IHC and IHC (fro).

Quick Overview for KIT antibody (ABIN212879)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This KIT antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: ACK4

Product Details anti-KIT Antibody

Specificity: Anti-mouse CD117 monoclonal antibody recognizes the receptor tyrosine kinase, c-kit. The ligand for this receptor is steel factor (stem cell factor), which exists in both soluble and membrane form. The interaction between steel factor and c-kit is essenti.

Purification: Protein G purified

Immunogen: IL-3 dependent mast cells derived from WB- +/+.

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo (0.2 μg/10 x10⁶), IHC, IHC-Fr

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.

Target Details for KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Alternative Name: C-Kit / CD117

Background: Name/Gene ID: KIT
Subfamily: PDGF Receptor
Family: Protein Kinase

Synonyms: KIT, C-Kit, CD117, PBT, Piebald trait, Piebald trait protein, Proto-oncogene c-Kit, SCFR, Soluble KIT variant 1, Tyrosine-protein kinase Kit, p145 c-kit, CD117 antigen

Gene ID: 3815

UniProt: P10721

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity