FZD7 antibody (C-Term)

Catalog No. ABIN213489

Product Details anti-FZD7 Antibody

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Bat, Monkey, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human FZD7 / Frizzled 7. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FZD1 (61 % ), FZD2 (61 %).

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Bat, Hamster, Elephant, Panda, Rabbit, Opossum (100%) Platypus (94%) Chicken, Xenopus (89%).

Purification: Immunoaffinity purified

Immunogen: Synthetic 18 amino acid peptide from C-terminus of human FZD7 / Frizzled 7. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Bat, Hamster, Elephant, Panda, Rabbit, Opossum (100%), Platypus (94%), Chicken, Xenopus (89%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: ELISA, IHC, IHC-P (15 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 15 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FZD7

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Alternative Name: FZD7 / Frizzled 7 (FZD7 Products)

Synonyms: FzE3 antibody, Fz-7 antibody, Xfz7 antibody, frizzled-7 antibody, frizzled7 antibody, frz-7 antibody, frz7 antibody, fz7 antibody, fzd7-a antibody, fzd7-b antibody, fze3 antibody, Fz7 antibody, cFz-7 antibody, fb38g02 antibody, fc44b09 antibody, fz13 antibody, fz7a antibody, fz7b antibody, wu:fb38g02 antibody, wu:fc44b09 antibody, zg13 antibody, frizzled class receptor 7 antibody, frizzled class receptor 7 L homeolog antibody, frizzled class receptor 7b antibody, FZD7 antibody, fzd7.L antibody, fzd7 antibody, Fzd7 antibody, fzd7b antibody

Background: Name/Gene ID: FZD7
Subfamily: Frizzled
Family: GPCR

Synonyms: FZD7, Frizzled family receptor 7, Frizzled homolog 7, Frizzled 7, Frizzled-7, FzE3, Fz-7, HFz7

Gene ID: 8324

Pathways: WNT Signaling, Stem Cell Maintenance