DSCR3 antibody (Middle Region)

Catalog No. ABIN2156719

Product Details anti-DSCR3 Antibody

Target: DSCR3 (Down Syndrome Critical Region Gene 3 (DSCR3))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Horse, Rabbit, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DSCR3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SAPQKGKFTP SPVDFTITPE TLQNVKERAL LPKFLLRGHL NSTNCVITQP

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DSCR3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DSCR3

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DSCR3

Target: DSCR3 (Down Syndrome Critical Region Gene 3 (DSCR3))

Alternative Name: DSCR3 (DSCR3 Products)

Synonyms: zgc:92243 antibody, DSCR3 antibody, DKFZp469M1432 antibody, MGC116512 antibody, DCRA antibody, DSCRA antibody, AW538125 antibody, Dcra antibody, DSCR3 arrestin fold containing antibody, Down syndrome critical region 3 antibody, down syndrome critical region protein 3 antibody, DSCR3 arrestin fold containing L homeolog antibody, Dscr3 antibody, DSCR3 antibody, dscr3 antibody, CpipJ_CPIJ008672 antibody, PITG_10989 antibody, dscr3.L antibody

Background: The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.
Alias Symbols: DCRA, DSCRA
Protein Size: 249

Molecular Weight: 27 kDa

Gene ID: 10311

NCBI Accession: XM_011529423, XP_011527725

UniProt: A8MTY9