Desmoplakin antibody

Catalog No. ABIN215767

Product Details anti-Desmoplakin Antibody

Target: Desmoplakin (DSP)

Reactivity: Human, Mouse, Rat, Cow, Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This Desmoplakin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Recognizes bovine Desmoplakin 1 at 250kD, reacts with the rod fragment of desmoplakin 1. Species cross-reactivity: human, rat, chicken, mouse. Reactivities on cultured human carcinoma cell lines: MCF-7, A-431, TR-146, bovine cells: MDBK, BMGE. Specifically detects tumors on primary and metastatic carcinoma, and meningioma. Shows distinct punctate membrane staining of epithelia.

Purification: Protein A purified

Immunogen: Bovine desmoplakin 1.

Type of Immunogen: Purified protein

Isotype: IgG1

Application Details

Application Notes: Approved: IHC, IHC-Fr (1:10), IHC-P (1:10)

Usage: Immunohistochemistry (frozen and paraffin): 1:10 with PBS,  pH 7.4, incubation time 1h at RT. Microwave treatment required.

Comment:

Target Species of Antibody: Bovine

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile ddH2O

Concentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.4, 0.09 % sodium azide, 0.5 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aviod frequent freeze thaws.

Storage: -20 °C

Storage Comment: Store at -20°C prior to reconstitution. After reconstitution aliquot and freeze at-20°C. Avoid freeze-thaw cycles.

Target Details for Desmoplakin

Target: Desmoplakin (DSP)

Alternative Name: DSP / Desmoplakin (DSP Products)

Synonyms: DP antibody, DPI antibody, DPII antibody, DSP antibody, dpi antibody, dpii antibody, 2300002E22Rik antibody, 5730453H04Rik antibody, AA407887 antibody, AA407888 antibody, AW109828 antibody, im:6911953 antibody, sb:cb570 antibody, wu:fc17a08 antibody, wu:fk73d01 antibody, desmoplakin antibody, Desmoplakin antibody, ORF113 antibody, desmoplakin a antibody, ORF112 DESMOPLAKIN antibody, orf102 antibody, orf91; similar to Cydia pomonella granulovirus orf112 antibody, ORF62 antibody, ORF-66 antibody, ORF57 antibody, agip105 antibody, similar to XcORF133; similar to HaGV desmoplakin antibody, desmoplakin L homeolog antibody, ORF96 antibody, DSP antibody, PhopGV104 antibody, ORF-59 desmoplakin antibody, desmop antibody, Dsp antibody, dsp antibody, desmoplakin antibody, dspa antibody, orf112 desmoplakin antibody, ClgVgp102 antibody, COGV_gp091 antibody, APNV_p087 antibody, CBNV_gp066 antibody, EONV_gp057 antibody, OLNV_gp066 antibody, AgipMNPV_gp105 antibody, HaMNV_gp106 antibody, EupsNPV_gp065 antibody, PsunGV_gp139 antibody, dsp.L antibody, ClanGV_gp096 antibody

Background: Name/Gene ID: DSP

Synonyms: DSP, Apeg-1, Desmoplakin II, DP, Desmoplakin I, DPI, Desmoplakin (DPI, DPII), KPPS2, PPKS2, Desmoplakin, DPII

Gene ID: 1832

UniProt: P15924

Pathways: Cell-Cell Junction Organization