Desmoplakin Products
(Desmoplakin (DSP))
Categories
Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus. [provided by RefSeq, Jul 2008].
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Featured Desmoplakin Categories
Desmoplakin Antibodies
High quality antibodies with extensive validation data.
Desmoplakin ELISA Kits
Reliable ELISA kits for a wide range of species.
Desmoplakin Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Desmoplakin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, WB, IP, ICC
Validations
- (7)
Cat. No.
ABIN7434746
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (5)
Cat. No.
ABIN7073719
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (4)
Cat. No.
ABIN7263625
Quantity
200 μL
Datasheet
Datasheet
Recommended Desmoplakin ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955369
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966346
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN512485
Quantity
96 tests
Datasheet
Datasheet
Recommended Desmoplakin Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122647
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7396043
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5709423
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Desmoplakin products
: "Activation of PKB/Akt and p44/42 by mechanical stretch utilizes desmosomal structures and the keratin filament." in: Journal of dermatological science, Vol. 89, Issue 3, pp. 241-247, (2018) (PubMed).: "Salivary proteomics in bisphosphonate-related osteonecrosis of the jaw." in: Oral diseases, (2013) (PubMed).
: "Laminin, gamma 2 (LAMC2): a promising new putative pancreatic cancer biomarker identified by proteomic analysis of pancreatic adenocarcinoma tissues." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 10, pp. 2820-32, (2013) (PubMed).
: "Desmoplakin acts as a tumor suppressor by inhibition of the Wnt/β-catenin signaling pathway in human lung cancer." in: Carcinogenesis, Vol. 33, Issue 10, pp. 1863-70, (2012) (PubMed).
: "Role of genetic testing in arrhythmogenic right ventricular cardiomyopathy/dysplasia." in: Clinical genetics, Vol. 77, Issue 1, pp. 37-48, (2010) (PubMed).
Synonyms and alternative names related to Desmoplakin
desmoplakin (DSP), desmoplakin (PhopGV104), desmoplakin (ORF-59 desmoplakin), Desmoplakin (desmop), desmoplakin (Dsp), desmoplakin (dsp), ORF113 (desmoplakin), desmoplakin (desmoplakin), desmoplakin a (dspa), ORF112 DESMOPLAKIN (orf112 desmoplakin), orf102 (ClgVgp102), orf91; similar to Cydia pomonella granulovirus orf112 (COGV_gp091), ORF62 (APNV_p087), ORF-66 (CBNV_gp066), ORF57 (EONV_gp057), desmoplakin (OLNV_gp066), agip105 (AgipMNPV_gp105), desmoplakin (HaMNV_gp106), desmoplakin (EupsNPV_gp065), similar to XcORF133; similar to HaGV desmoplakin (PsunGV_gp139), desmoplakin L homeolog (dsp.L), ORF96 (ClanGV_gp096), 2300002E22Rik, 5730453H04Rik, AA407887, AA407888, AW109828, DP, DPI, dpi, DPII, dpii, DSP, im:6911953, sb:cb570, wu:fc17a08, wu:fk73d01Protein level used designations for Desmoplakin
- 250/210 kDa paraneoplastic pemphigus antigen
- desmoplakin I
- desmoplakin II
- desmoplakin
- Desmoplakin
- putative desmoplakin
- desmoplakin I/II
- desmosomal cytoskeletal connector molecule
- fk73d01
- ORF112 DESMOPLAKIN
- agip105
- desmoplakin-related protein
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