DRD3 antibody (3rd Cytoplasmic Domain)

Catalog No. ABIN5674035

Product Details anti-DRD3 Antibody

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Binding Specificity: 3rd Cytoplasmic Domain

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: The 19 AA human D3R peptide showed no significant sequence homology with other dopamine receptors (D1, D2, D4 or D5). It has sequence homology of 94 % with monkey (18/19 AA) and 73 % with mouse/rat (14/19 AA) D3R receptors (1-2). Antibody cross-reactivity with D3R from various species is not known.

Purification: Immunoaffinity purified

Immunogen: A 19 AA Peptide (Control peptide) sequence from the human D3 receptor within the 3rd cytoplasmic domain. The peptide was coupled to KLH.

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (0.5 - 1 μg/mL), IHC (2 - 10 μg/mL), WB (1 - 10 μg/mL)

Usage: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Western Blot: 1-10 μg/mL. Using ECL. ELISA: 0.5-1 μg/mL. Control peptide can be used to coat ELISA plates at 1 μg/mL. Immunohistochemistry: 2-10 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % BSA, 0.1 % sodium azide, 40 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for DRD3

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Alternative Name: DRD3 / Dopamine Receptor D3 (DRD3 Products)

Synonyms: DRD3 antibody, D3R antibody, D3DR antibody, ETM1 antibody, FET1 antibody, dopamine receptor D3 antibody, drd3 antibody, DRD3 antibody, Drd3 antibody

Background: Name/Gene ID: DRD3
Subfamily: Dopamine
Family: GPCR

Synonyms: DRD3, D3 dopamine receptor, D3DR, Dopamine 3 receptor, Dopamine receptor D3, D3nf, Essential tremor 1, ETM1, FET1, D(3) dopamine receptor, Dopamine D3 receptor

Gene ID: 1814

UniProt: P35462

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity