Superoxide dismutase copper chaperone antibody (AA 201-274) (Cy5.5)
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- Target See all Superoxide dismutase copper chaperone (CCS) Antibodies
- Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))
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Binding Specificity
- AA 201-274
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Superoxide dismutase copper chaperone antibody is conjugated to Cy5.5
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SOD4
- Isotype
- IgG
- Top Product
- Discover our top product CCS Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))
- Alternative Name
- SOD4/CCS (CCS Products)
- Synonyms
- ccs antibody, MGC82563 antibody, CCS antibody, DDBDRAFT_0189222 antibody, DDBDRAFT_0238038 antibody, DDB_0189222 antibody, DDB_0238038 antibody, ATCCS antibody, COPPER/ZINC SUPEROXIDE DISMUTASE COPPER CHAPERONE antibody, F5O11.26 antibody, F5O11_26 antibody, copper chaperone for SOD1 antibody, Ccsd antibody, copper chaperone for superoxide dismutase L homeolog antibody, copper chaperone for superoxide dismutase antibody, copper chaperone for SOD1 antibody, ccs.L antibody, ccs antibody, CCS antibody, LOC552629 antibody, Ccs antibody
- Background
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Synonyms: CCS, CCS_HUMAN, Copper chaperone for superoxide dismutase, MGC138260, SOD 4, SOD4, Superoxide dismutase copper chaperone.
Background: Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.
- Gene ID
- 9973
- Pathways
- Transition Metal Ion Homeostasis
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