ABL1 antibody (pTyr245)

Catalog No. ABIN6735184

Product Details anti-ABL1 Antibody

Target: ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

Binding Specificity: pTyr245

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABL1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human c-Abl. Mouse (92% homologous) c-Abl has not been tested, but is expected to react.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic phosphopeptide derived from a region of human c-Abl that contains tyrosine 245. Note: there are two widely expressed forms of c-Abl produced by alternative splicing, known as 1a and 1b (the more commonly used form). The corresponding phosphorylation site from 1a is tyrosine 226.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS (without Mg2+, Ca2+), 1 mg/mL BSA (IgG, protease free), pH 7.2, 0.1% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.

Target Details for ABL1

Target: ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

Alternative Name: ABL1 / C-ABL (ABL1 Products)

Synonyms: ABL antibody, JTK7 antibody, bcr/abl antibody, c-ABL antibody, p150 antibody, v-abl antibody, AI325092 antibody, Abl antibody, E430008G22Rik antibody, c-Abl antibody, ABL proto-oncogene 1, non-receptor tyrosine kinase antibody, c-abl oncogene 1, non-receptor tyrosine kinase antibody, Tyrosine-protein kinase abl-1 antibody, ABL1 antibody, Abl1 antibody, abl-1 antibody, abl1 antibody

Background: Standard Gene Symbol: ABL1, Gene Family: Protein Kinase, Gene Subfamily: Abl, Synonyms: ABL1, Bcr/c-abl oncogene protein, Bcr-Abl, Bcr/abl, C-ABL, ABL, JTK7, p150, Tyrosine-protein kinase ABL1, Proto-oncogene c-Abl, V-abl

Gene ID: 25

UniProt: P00519

Pathways: Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism