S100A8 antibody

Catalog No. ABIN228787

This Mouse Monoclonal antibody specifically detects S100A8 in IHC and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Pig, Dog, Cat, Monkey and Guinea Pig.

Quick Overview for S100A8 antibody (ABIN228787)

Target: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Reactivity: Human, Mouse, Rat, Pig, Dog, Cat, Monkey, Guinea Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This S100A8 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-S100A8 Antibody

Specificity: Recognizes human neutrophils, monocytes, macrophages and squamous mucosal epithelia. Has been shown as an important marker for identifying macrophages in tissue sections. Species cross-reactivity: baboon, monkey, porcine, feline, canine, guinea pig, rat and mouse.

Purification: Protein G purified

Immunogen: Affinity purified monocyte membrane preparation. Cellular Localization: Cytoplasmic.

Isotype: IgG1

Application Details

Application Notes: Approved: IHC, IHC-P

Usage: Suitable for use in Immunohistochemistry. Immunohistochemistry: 1:1000 for 20 min at RT. For staining of formalin-fixed paraffin tissues, digest sections with trypsin at 1 mg/mL PBS for 10 min. at 37?C. Positive control: Tonsil, lymph node or spleen.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.2 % BSA, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for S100A8

Target: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Alternative Name: S100A8 / MRP8

Background: Name/Gene ID: S100A8

Synonyms: S100A8, 60B8AG, CFAG, CAGA, Calgranulin A, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, CGLA, L1Ag, NIF, p8, Protein S100-A8, MRP8, Urinary stone protein band A, CP-10, MA387, MRP-8

Gene ID: 6279

UniProt: P05109

Pathways: Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins