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Antibodies
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anti-ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) antibody
ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) antibody
| Antigen |
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| Synonyms |
Centd2, MGC176140, mKIAA0782, 2410002L19Rik, CENTD2, KIAA0782, ARAP1, centd2, Ci-ArfGAP-8 |
| Clonality |
Monoclonal (ARAP1-2) |
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Host
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Reactivity
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Application
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Alternatives Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
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| Catalog no. |
ABIN238383 |
| Quantity |
0.1 mg (1.0 mg/ml) |
| Price |
290.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: KIAA0782, Centaurin-delta-2, Arf-GAP, Rho-GAP domain, ANK repeat and PHdomain-containing protein 1
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Alternative name
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ARAP1 / CENTD2
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Swiss-Prot
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Q96P48
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Immunogen
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His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1
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Cross-Reactivity
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Human
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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ARAP1-2
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Description
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ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAPand RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptorseems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) andis important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to theplasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.
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Specificity
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The antibody ARAP1-2 reacts with C-terminal part of ARAP1, a 160 kDa adaptor protein. Species: Human. Others not tested.
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Application Notes
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Suitable for Western Blotting (2 μg/ml). Immunoprecipitation. Immunocytochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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1.0 mg/ml
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Purification
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Aff - Purified
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Buffer
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PBS, pH 7.4 with 15 mM sodium azide as preservative.
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid freeze/thaw cycles. Shelf life: One year from despatch.
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Restrictions
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For Research Use only
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Alternatives for antigen "ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1)", type "Antibodies"