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ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) antibody

Antigen

ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1)

Synonyms Centd2, MGC176140, mKIAA0782, 2410002L19Rik, CENTD2, KIAA0782, ARAP1, centd2, Ci-ArfGAP-8
Clonality Monoclonal (ARAP1-2)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Application
Alternatives Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
Catalog no. ABIN238383
Quantity 0.1 mg  (1.0 mg/ml)
Price 290.00 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information

Characteristics Synonyms: KIAA0782, Centaurin-delta-2, Arf-GAP, Rho-GAP domain, ANK repeat and PHdomain-containing protein 1
Alternative name ARAP1 / CENTD2
Swiss-Prot Q96P48
Immunogen His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1
Cross-Reactivity Human
Isotype IgG1  (Matching secondary antibodies)
Clone ARAP1-2
Description ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAPand RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptorseems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) andis important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to theplasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.
Specificity The antibody ARAP1-2 reacts with C-terminal part of ARAP1, a 160 kDa adaptor protein. Species: Human. Others not tested.

Application Details

Application Notes Suitable for Western Blotting (2 μg/ml). Immunoprecipitation. Immunocytochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 1.0 mg/ml
Purification Aff - Purified
Buffer PBS, pH 7.4 with 15 mM sodium azide as preservative.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid freeze/thaw cycles. Shelf life: One year from despatch.
Restrictions For Research Use only

Alternatives

Alternatives for antigen "ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1)", type "Antibodies"
Hosts Goat (3), Mouse (3)
Reactivities Human (4)
Applications Western Blotting (WB) (3), Immunoprecipitation (IP) (2), ELISA (1), ELISA (Detection) (1), Enzyme Immunoassay (EIA) (1), Immunocytochemistry (ICC) (1), Immunofluorescence (IF) (1)