IGFBP3 antibody (Insulin-Like Growth Factor Binding Protein 3) (Internal Region)

Details for Product anti-IGFBP3 Antibody No. ABIN238551, Supplier: Log in to see
Antigen
  • IGFBP-3
  • zgc:91788
  • IGFBP3
  • igfbp3
  • BP-53
  • IBP3
  • AI649005
  • IGgfbp3
  • IGF-BP3
  • insulin-like growth factor binding protein 3
  • insulin-like growth factor binding protein-3
  • igfbp3
  • IGFBP-3
  • IGFBP3
  • LOC100220315
  • LOC100305016
  • Igfbp3
Alternatives
anti-Human IGFBP3 antibody for Enzyme Immunoassay
Epitope
Internal Region
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9
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6
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5
3
3
3
3
2
2
1
1
1
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Reactivity
Human
196
80
42
10
8
6
4
4
2
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2
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Host
Goat
164
37
17
16
Clonality
Polyclonal
Conjugate
This IGFBP3 antibody is un-conjugated
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12
9
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1
1
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1
Method Type
Peptide ELISA
Application
ELISA, Western Blotting (WB)
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110
74
42
13
6
6
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3
3
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2
1
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Options
Supplier
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Supplier Product No.
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Immunogen Peptide with sequence C-RYKVDYESQSTDTQN, from the internal region of the protein sequence according to NP_001013416.1, NP_000589.2.
Blocking Peptide Blocking peptide for this product available: ABIN369846
Specificity This antibody is expected to recognise both reported isoforms (NP_001013416.1 and NP_000589.2).
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name IGFBP3 (IGFBP3 Antibody Abstract)
Background Synonyms: IGFBP3, insulin-like growth factor binding protein 3, tcag7.703, BP-53, IBP3, IGF-binding protein 3, acid stable subunit of the 140 K IGF complex, binding protein 29, binding protein 53, growth hormone-dependent binding protein
Gene ID 3486, 16009, 24484
NCBI Accession NP_000589, NP_001013416
Research Area Cardiovascular, Atherosclerosis, Angiogenesis, Apoptosis/Necrosis, Hormones, Diabetes, Metabolism, Growth Factors
Pathways Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
Application Notes ELISA: antibody detection limit dilution 1:64000.
Western blot: Approx 28 kDa band observed in Human Breast cancer lysates (calculated MW of 31.7 kDa according to NP_001013416.1 and 32.2 kDa according to NP_000589.2). Recommended concentration: 0.02-0.06 µg/mL. An additional band of 50 kDa was consistently observed, however this band was not blocked by the immunizing peptide and it is therefore a non-specific signal. We call for caution when used for other assays than Western blot.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (Internal Region) antibody (ABIN238551) ABIN238551 (0.02µg/ml) staining of Human Breast cancer lysate (35µg protein in RIPA b...
Background publications Lin, Manson, Lee, Cook, Buring, Zhang: "Intakes of calcium and vitamin D and breast cancer risk in women." in: Archives of internal medicine, Vol. 167, Issue 10, pp. 1050-9, 2007 (PubMed).

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