GFRA1 antibody

Catalog No. ABIN2431438

Product Details anti-GFRA1 Antibody

Target: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFRA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity purification

Immunogen: Synthetic peptide of human GFRA1

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GFRA1

Target: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Alternative Name: GFRA1 (GFRA1 Products)

Synonyms: gdnfr antibody, ret1l antibody, retl1 antibody, trnr1 antibody, gdnfra antibody, MGC122616 antibody, gfr-alpha-1 antibody, GDNFR antibody, GDNFRA antibody, GFR-ALPHA-1 antibody, RET1L antibody, RETL1 antibody, TRNR1 antibody, GDNFRALPHA antibody, GFRA1 antibody, AU042498 antibody, gfralpha1a antibody, zgc:110129 antibody, GDNF family receptor alpha 1 antibody, glial cell line derived neurotrophic factor family receptor alpha 1 antibody, gdnf family receptor alpha 1a antibody, gfra1 antibody, GFRA1 antibody, Gfra1 antibody, gfra1a antibody

Background: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.

Molecular Weight: Calculated MW: 51 kDa

NCBI Accession: NP_005255