GBA3 antibody (AA 1-150, AA 370-469)
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- Target See all GBA3 Antibodies
- GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))
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Binding Specificity
- AA 1-150, AA 370-469
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GBA3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Homo sapiens glucosidase, beta, acid 3 (cytosolic) (GBA3), transcript variant 1
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Human recombinant protein fragment corresponding to amino acids 1-150 and AA 370-469 of human GBA3(NP_066024) produced in E.coli.
- Clone
- 3E8
- Isotype
- IgG1
- Top Product
- Discover our top product GBA3 Primary Antibody
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- Application Notes
- WB 1:2000, IHC 1:150,
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))
- Alternative Name
- GBA3 (GBA3 Products)
- Synonyms
- im:6912508 antibody, CBG antibody, CBGL1 antibody, GLUC antibody, KLRP antibody, glucosylceramidase beta 3 antibody, glucosidase, beta, acid 3 (gene/pseudogene) antibody, glucosidase, beta, acid 3 (cytosolic) antibody, cytosolic beta-glucosidase antibody, glucosylceramidase beta 3 (gene/pseudogene) antibody, Gba3 antibody, gba3 antibody, GBA3 antibody, LOC100344458 antibody
- Background
- GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).
- Molecular Weight
- 53.5 kDa
- Gene ID
- 57733
- NCBI Accession
- NM_020973
- HGNC
- 57733
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