PSMB7 antibody (AA 58-277)
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- Target See all PSMB7 Antibodies
- PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))
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Binding Specificity
- AA 58-277
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Reactivity
- Human, Mouse, Monkey
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PSMB7 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Homo sapiens proteasome (prosome, macropain) subunit, beta type, 7 (PSMB7)
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Human recombinant protein fragment corresponding to amino acids 58-277 of human PSMB7(NP_002790) produced in E.coli.
- Clone
- 1E1
- Isotype
- IgG1
- Top Product
- Discover our top product PSMB7 Primary Antibody
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- Application Notes
- WB 1:500~2000, IHC 1:150,
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))
- Alternative Name
- PSMB7 (PSMB7 Products)
- Synonyms
- DDBDRAFT_0185624 antibody, DDBDRAFT_0232933 antibody, DDB_0185624 antibody, DDB_0232933 antibody, AU020723 antibody, MC14 antibody, Z antibody, 20S proteasome subunit beta-7 antibody, proteasome (prosome, macropain) subunit, beta type, 7 S homeolog antibody, proteasome subunit beta 7 antibody, proteasome (prosome, macropain) subunit, beta type, 7 antibody, proteasome (prosome, macropain) subunit, beta type 7 antibody, psmB7 antibody, psmb7.S antibody, PSMB7 antibody, Psmb7 antibody
- Background
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).
- Molecular Weight
- 29.8 kDa
- Gene ID
- 5695
- NCBI Accession
- NM_002799
- HGNC
- 5695
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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