SLC26A3 antibody

Catalog No. ABIN2457907

Product Details anti-SLC26A3 Antibody

Target: SLC26A3 (Solute Carrier Family 26, Member 3 (SLC26A3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC26A3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC26A3.

Application Details

Application Notes: SLC26A3 antibody can be used for detection of SLC26A3 by ELISA at 1:312500. SLC26A3 antibody can be used for detection of SLC26A3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SLC26A3 antibody at -20 °C.

Target Details for SLC26A3

Target: SLC26A3 (Solute Carrier Family 26, Member 3 (SLC26A3))

Alternative Name: SLC26A3 (SLC26A3 Products)

Synonyms: CLD antibody, DRA antibody, 9030623B18Rik antibody, 9130013M11Rik antibody, AV376035 antibody, Dra antibody, si:dkey-31f5.2 antibody, SLC26A3 antibody, solute carrier family 26 member 3 antibody, solute carrier family 26, member 3 antibody, solute carrier family 26 (anion exchanger), member 3 antibody, SLC26A3 antibody, Slc26a3 antibody, slc26a3.1 antibody

Background: SLC26A3 is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.The protein encoded by this gene is a transmembrane glycoprotein that functions as a sulfate transporter. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. Mutations in this gene have been associated with congenital chloride diarrhea. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 84 kDa

Gene ID: 1811

NCBI Accession: NP_000102

UniProt: P40879