Kv2.1/KCNB1 antibody

Catalog No. ABIN2458059

Product Details anti-Kv2.1/KCNB1 Antibody

Target: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kv2.1/KCNB1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNB1.

Application Details

Application Notes: KCNB1 antibody can be used for detection of KCNB1 by ELISA at 1:62500. KCNB1 antibody can be used for detection of KCNB1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KCNB1 antibody at -20 °C.

Target Details for Kv2.1/KCNB1

Target: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Alternative Name: KCNB1 (KCNB1 Products)

Synonyms: KCNB1 antibody, Kcnb1 antibody, Kcr1-1 antibody, Kv2.1 antibody, Shab antibody, DRK1PC antibody, DRK1 antibody, KV2.1 antibody, h-DRK1 antibody, potassium voltage-gated channel subfamily B member 1 antibody, potassium voltage-gated channel, Shab-related subfamily, member 1 antibody, potassium channel, voltage gated Shab related subfamily B, member 1 antibody, potassium voltage gated channel, Shab-related subfamily, member 1 antibody, KCNB1 antibody, kcnb1 antibody, LOC100541632 antibody, Kcnb1 antibody

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 96 kDa

Gene ID: 3745

NCBI Accession: NP_004966

UniProt: Q14721

Pathways: Synaptic Membrane