LSS antibody

Catalog No. ABIN2458612

Product Details anti-LSS Antibody

Target: LSS (Lanosterol Synthase (2,3-Oxidosqualene-Lanosterol Cyclase) (LSS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LSS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LSS.

Application Details

Application Notes: LSS antibody can be used for detection of LSS by ELISA at 1:312500. LSS antibody can be used for detection of LSS by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store LSS antibody at -20 °C.

Target Details for LSS

Target: LSS (Lanosterol Synthase (2,3-Oxidosqualene-Lanosterol Cyclase) (LSS))

Alternative Name: LSS (LSS Products)

Synonyms: OSC antibody, 2810025N20Rik antibody, BC029082 antibody, D10Ertd116e antibody, Osc antibody, xlss antibody, Tb07.27E10.490 antibody, NCU01119.1 antibody, lanosterol synthase antibody, lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) antibody, putative lanosterol synthase antibody, Lanosterol synthase, putative antibody, LSS antibody, Lss antibody, lss antibody, CND02520 antibody, Tc00.1047053506825.170 antibody, Tc00.1047053508175.70 antibody, Tb927.7.5230 antibody, NCU01119 antibody, LMJF_06_0650 antibody, CGB_D5080W antibody, LOC100636608 antibody

Background: LSS catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. It is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Two transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Two transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 83 kDa

Gene ID: 4047

NCBI Accession: NP_002331

UniProt: P48449