Stanniocalcin 1 antibody

Catalog No. ABIN2458624

Product Details anti-Stanniocalcin 1 Antibody

Target: Stanniocalcin 1 (STC1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stanniocalcin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STC1.

Application Details

Application Notes: STC1 antibody can be used for detection of STC1 by ELISA at 1:62500. STC1 antibody can be used for detection of STC1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store STC1 antibody at -20 °C.

Target Details for Stanniocalcin 1

Target: Stanniocalcin 1 (STC1)

Alternative Name: STC1 (STC1 Products)

Synonyms: STC antibody, Stc antibody, stc1 antibody, MGC82280 antibody, STC1 antibody, zgc:153307 antibody, LOC777959 antibody, stanniocalcin 1 antibody, stanniocalcin 1 L homeolog antibody, stanniocalcin 1 S homeolog antibody, STC1 antibody, Stc1 antibody, stc1.L antibody, stc1.S antibody, stc1 antibody, LOC777959 antibody

Background: STC1 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. It contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate.This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 26 kDa

Gene ID: 6781

NCBI Accession: NP_003146

UniProt: P52823

Pathways: Hormone Activity