MAGEA4 antibody

Catalog No. ABIN2459747

Product Details anti-MAGEA4 Antibody

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAGEA4.

Application Details

Application Notes: MAGEA4 antibody can be used for detection of MAGEA4 by ELISA at 1:312500. MAGEA4 antibody can be used for detection of MAGEA4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MAGEA4 antibody at -20 °C.

Target Details for MAGEA4

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Alternative Name: MAGEA4 (MAGEA4 Products)

Synonyms: Mage-a4 antibody, MAGEA4 antibody, CT1.4 antibody, MAGE-41 antibody, MAGE-X2 antibody, MAGE4 antibody, MAGE4A antibody, MAGE4B antibody, melanoma antigen, family A, 4 antibody, MAGE family member A4 antibody, Magea4 antibody, MAGEA4 antibody

Background: MAGEA4 is a member of the MAGEA family. The members of this family are proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.

Molecular Weight: 35 kDa

Gene ID: 4103

NCBI Accession: NP_001011548

UniProt: P43358