GTPBP4 antibody

Catalog No. ABIN2459824

Product Details anti-GTPBP4 Antibody

Target: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTPBP4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GTPBP4.

Application Details

Application Notes: GTPBP4 antibody can be used for detection of GTPBP4 by ELISA at 1:2500. GTPBP4 antibody can be used for detection of GTPBP4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GTPBP4 antibody at -20 °C.

Target Details for GTPBP4

Target: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Alternative Name: GTPBP4 (GTPBP4 Products)

Synonyms: CRFG antibody, NGB antibody, NOG1 antibody, 2610028C09Rik antibody, Crfg antibody, Gtpbp3 antibody, Nog1 antibody, fi28d07 antibody, zgc:55757 antibody, wu:fi28d07 antibody, xgb antibody, GTP binding protein 4 antibody, GTP binding protein 4 L homeolog antibody, GTPBP4 antibody, Gtpbp4 antibody, gtpbp4 antibody, CC1G_14285 antibody, gtpbp4.L antibody

Background: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.

Molecular Weight: 74 kDa

Gene ID: 23560

NCBI Accession: NP_036473

UniProt: Q9BZE4