FAM120A antibody

Catalog No. ABIN2459850

Product Details anti-FAM120A Antibody

Target: FAM120A (Family with Sequence Similarity 120A (FAM120A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM120A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FAM120A.

Application Details

Application Notes: FAM120A antibody can be used for detection of FAM120A by ELISA at 1:312500. FAM120A antibody can be used for detection of FAM120A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FAM120A antibody at -20 °C.

Target Details for FAM120A

Target: FAM120A (Family with Sequence Similarity 120A (FAM120A))

Alternative Name: FAM120A (FAM120A Products)

Synonyms: MGC89333 antibody, fam120a antibody, C9orf10 antibody, Ossa antibody, DNAPTP1 antibody, DNAPTP5 antibody, OSSA antibody, RGD1306643 antibody, family with sequence similarity 120A antibody, family with sequence similarity 120, member A antibody, fam120a antibody, Fam120a antibody, FAM120A antibody

Background: FAM120A may participate in mRNA transport in the cytoplasm. FAM120A is the critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A binds RNA and promotes the secretion of IGF-II. It may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.

Molecular Weight: 122 kDa

Gene ID: 23196

NCBI Accession: NP_055427

UniProt: Q9NZB2