CCBP2 antibody

Catalog No. ABIN2460191

Product Details anti-CCBP2 Antibody

Target: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCBP2.

Application Details

Application Notes: CCBP2 antibody can be used for detection of CCBP2 by ELISA at 1:62500. CCBP2 antibody can be used for detection of CCBP2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CCBP2 antibody at -20 °C.

Target Details for CCBP2

Target: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Alternative Name: CCBP2 (CCBP2 Products)

Synonyms: CCBP2 antibody, CCR10 antibody, CCR9 antibody, CMKBR9 antibody, D6 antibody, hD6 antibody, Ccbp2 antibody, LOC733624 antibody, A130091K22Rik antibody, Cmkbr10 antibody, GPR-9-6 antibody, AI464239 antibody, Cmkbr9 antibody, atypical chemokine receptor 2 antibody, atypical chemokine receptor 2-like antibody, chemokine receptor D6 antibody, chemokine (C-C motif) receptor 9 antibody, C-C motif chemokine receptor 9 antibody, ACKR2 antibody, Ackr2 antibody, LOC100219492 antibody, LOC733624 antibody, Ccr9 antibody, CCR9 antibody

Background: CCBP2 is a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown.This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

Molecular Weight: 43 kDa

Gene ID: 1238

NCBI Accession: NP_001287

UniProt: O00590