CIAO1 antibody

Catalog No. ABIN2460941

Product Details anti-CIAO1 Antibody

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIAO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WDR39.

Application Details

Application Notes: WDR39 antibody can be used for detection of WDR39 by ELISA at 1:62500. WDR39 antibody can be used for detection of WDR39 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store WDR39 antibody at -20 °C.

Target Details for CIAO1

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Alternative Name: WDR39 (CIAO1 Products)

Synonyms: CG12797 antibody, Dmel\\CG12797 antibody, DDBDRAFT_0190506 antibody, DDBDRAFT_0266672 antibody, DDB_0190506 antibody, DDB_0266672 antibody, CIA1 antibody, WDR39 antibody, AW210570 antibody, Wdr39 antibody, wdr39 antibody, zgc:55911 antibody, zgc:77394 antibody, CG12797 gene product from transcript CG12797-RA antibody, WD40 protein Ciao1 antibody, CIAO1 antibody, WD40 repeat-containing protein antibody, cytosolic iron-sulfur assembly component 1 antibody, cytosolic iron-sulfur protein assembly 1 antibody, Ciao1 antibody, cgd1_2230 antibody, CC1G_05316 antibody, ciao1 antibody, CIAO1 antibody

Background: WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.

Molecular Weight: 38 kDa

Gene ID: 9391

NCBI Accession: NP_004795

UniProt: O76071