WNT16 antibody

Catalog No. ABIN2462378

Product Details anti-WNT16 Antibody

Target: WNT16 (Wingless-Type MMTV Integration Site Family, Member 16 (WNT16))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT16 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WNT16.

Application Details

Application Notes: WNT16 antibody can be used for detection of WNT16 by ELISA at 1:312500. WNT16 antibody can be used for detection of WNT16 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store WNT16 antibody at -20 °C.

Target Details for WNT16

Target: WNT16 (Wingless-Type MMTV Integration Site Family, Member 16 (WNT16))

Alternative Name: WNT16 (WNT16 Products)

Synonyms: zgc:77293 antibody, E130309I19Rik antibody, Wnt family member 16 antibody, wingless-type MMTV integration site family, member 16 antibody, WNT16 antibody, wnt16 antibody, Wnt16 antibody

Background: WNT proteins are secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT16 contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen.

Molecular Weight: 38 kDa, 40 kDa

Gene ID: 51384

NCBI Accession: NP_476509

UniProt: Q9UBV4

Pathways: WNT Signaling