SYVN1 antibody
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- Target See all SYVN1 Antibodies
- SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SYVN1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SYVN1.
- Top Product
- Discover our top product SYVN1 Primary Antibody
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- Application Notes
- SYVN1 antibody can be used for detection of SYVN1 by ELISA at 1:312500. SYVN1 antibody can be used for detection of SYVN1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SYVN1 antibody at -20 °C.
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- Target
- SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
- Alternative Name
- SYVN1 (SYVN1 Products)
- Synonyms
- DER3 antibody, HRD1 antibody, hrd1 antibody, 1200010C09Rik antibody, AW211966 antibody, C85322 antibody, D530017H19Rik antibody, Hrd1 antibody, RGD1310488 antibody, syvn1 antibody, syvn1-a antibody, syvn1-b antibody, wu:fk91f10 antibody, zgc:55735 antibody, zgc:77108 antibody, synoviolin 1 antibody, synovial apoptosis inhibitor 1, synoviolin antibody, synoviolin 1 S homeolog antibody, SYVN1 antibody, syvn1 antibody, Syvn1 antibody, syvn1.S antibody
- Background
- SYVN1 is a protein involved in endoplasmic reticulum (ER)-associated degradation. The protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins.This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms.
- Molecular Weight
- 67 kDa
- Gene ID
- 84447
- NCBI Accession
- NP_115807
- UniProt
- Q86TM6
- Pathways
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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