DYNC1I1 antibody

Catalog No. ABIN2463493

Product Details anti-DYNC1I1 Antibody

Target: DYNC1I1 (Dynein, Cytoplasmic 1, Intermediate Chain 1 (DYNC1I1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYNC1I1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DYNC1I1.

Application Details

Application Notes: DYNC1I1 antibody can be used for detection of DYNC1I1 by ELISA at 1:62500. DYNC1I1 antibody can be used for detection of DYNC1I1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DYNC1I1 antibody at -20 °C.

Target Details for DYNC1I1

Target: DYNC1I1 (Dynein, Cytoplasmic 1, Intermediate Chain 1 (DYNC1I1))

Alternative Name: DYNC1I1 (DYNC1I1 Products)

Synonyms: Dnci1 antibody, Dncic1 antibody, DH IC-1 antibody, DHIC-1 antibody, DIC antibody, IC74 antibody, DNCI1 antibody, DNCIC1 antibody, dynein cytoplasmic 1 intermediate chain 1 antibody, Dync1i1 antibody, DYNC1I1 antibody

Background: DYNC1I1 belongs to the dynein intermediate chain family. It contains 7 WD repeats. The intermediate chains seem to help dynein bind to dynactin 150 kDa component. DYNC1I1 may play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.

Molecular Weight: 73 kDa

Gene ID: 1780

NCBI Accession: NP_004402

UniProt: O14576