RGS3 antibody

Catalog No. ABIN2463703

Product Details anti-RGS3 Antibody

Target: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RGS3.

Application Details

Application Notes: RGS3 antibody can be used for detection of RGS3 by ELISA at 1:62500. RGS3 antibody can be used for detection of RGS3 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RGS3 antibody at -20 °C.

Target Details for RGS3

Target: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Alternative Name: RGS3 (RGS3 Products)

Synonyms: RGS3 antibody, MGC115680 antibody, C2PA antibody, RGP3 antibody, 4930506N09Rik antibody, C2PA-RGS3 antibody, C2pa antibody, PDZ-RGS3 antibody, RGS3S antibody, SRB-RGS antibody, regulator of G protein signaling 3 antibody, regulator of G-protein signaling 3 L homeolog antibody, regulator of G-protein signaling 3 antibody, RGS3 antibody, rgs3.L antibody, Rgs3 antibody

Background: RGS3 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known.

Molecular Weight: 101 kDa

Gene ID: 5998

NCBI Accession: NP_570613

UniProt: P49796

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling