PSMB2 antibody

Catalog No. ABIN2463959

Product Details anti-PSMB2 Antibody

Target: PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMB2.

Application Details

Application Notes: PSMB2 antibody can be used for detection of PSMB2 by ELISA at 1:312500. PSMB2 antibody can be used for detection of PSMB2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PSMB2 antibody at -20 °C.

Target Details for PSMB2

Target: PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))

Alternative Name: PSMB2 (PSMB2 Products)

Synonyms: HC7-I antibody, 19.m02268 antibody, DDBDRAFT_0190287 antibody, DDBDRAFT_0232958 antibody, DDB_0190287 antibody, DDB_0232958 antibody, Psmb2 antibody, ACYPI004276 antibody, AU045357 antibody, AW108089 antibody, C7-I antibody, D4Wsu33e antibody, zgc:92282 antibody, proteasome subunit beta 2 antibody, proteasome subunit beta type 2 antibody, proteasome beta 2 subunit antibody, putative proteasome beta 2 subunit antibody, 20S proteasome subunit beta-2 antibody, proteasome (prosome, macropain) subunit, beta type 2 antibody, proteasome subunit beta 2 L homeolog antibody, PSMB2 antibody, CNC04990 antibody, Tc00.1047053510287.30 antibody, Tc00.1047053503891.100 antibody, Tc00.1047053508461.430 antibody, LBRM_34_3820 antibody, LBRM_35_0400 antibody, BBOV_I004450 antibody, LMJF_36_0320 antibody, psmB2 antibody, Psmb2 antibody, psmb2 antibody, psmb2.L antibody

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB2 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.

Molecular Weight: 23 kDa

Gene ID: 5690

NCBI Accession: NP_002785

UniProt: P49721

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA