SH3GL1 antibody (AA 1-360)

Catalog No. ABIN2468136

Product Details anti-SH3GL1 Antibody

Target: SH3GL1 (SH3-Domain GRB2-Like 1 (SH3GL1))

Binding Specificity: AA 1-360

Reactivity: Human, Rat, Mouse

Host: Chicken

Clonality: Polyclonal

Conjugate: This SH3GL1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Immunoaffinity Purified

Application Details

Application Notes: SH3-containing Grb-2-like 1 protein antibody can be used for the detection of SH3-containing Grb-2-like 1 protein by Western Blot.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Preservative: Without preservative

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Storage Comment: SH3GL1 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Target Details for SH3GL1

Target: SH3GL1 (SH3-Domain GRB2-Like 1 (SH3GL1))

Alternative Name: SH3GL1 (SH3GL1 Products)

Synonyms: CNSA1 antibody, EEN antibody, SH3D2B antibody, SH3P8 antibody, C77078 antibody, Sh3d2b antibody, cb831 antibody, sh3gl1 antibody, MGC78966 antibody, MGC130739 antibody, sh3gl1b antibody, wu:fd12b05 antibody, wu:fy33c10 antibody, zgc:56637 antibody, SH3 domain containing GRB2 like 1, endophilin A2 antibody, SH3-domain GRB2-like 1 antibody, SH3-domain GRB2-like 1b antibody, SH3-domain GRB2-like 1 L homeolog antibody, SH3-domain GRB2-like 1a antibody, SH3GL1 antibody, Sh3gl1 antibody, sh3gl1b antibody, sh3gl1.L antibody, sh3gl1 antibody, sh3gl1a antibody

Background: SH3GL1 may play a regulatory role in synaptic vesicle recycling. It interacts with SYNJ1 and DNM1 through its SH3 domain with the proline-rich region of mixed lineage Leukemia (MLL) in either the fusion or the normal MLL protein. This protein is located in cytoplasmic, and peripheral membrane protein associated with internal membranes. Concentrated in presynaptic nerve terminals in neurons (By similarity). It s expressed ubiquitously. Higher expression in pancreas, placenta, prostate, testis and uterus. In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene.

Molecular Weight: 39.8 kDa (calculated)

Gene ID: 6455

NCBI Accession: NP_003016

UniProt: Q99961