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CXCR4 antibody
CXCR4
Reactivity: Human, Monkey, Baboon, Chimpanzee
IHC, FACS, IF
Host: Mouse
Monoclonal
12G5
unconjugated
Product Details anti-CXCR4 Antibody
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Target
See all CXCR4 Antibodies
CXCR4
(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
Reactivity
All reactivities for CXCR4 antibodies
Human, Monkey, Baboon, Chimpanzee
Host
All hosts for CXCR4 antibodies
Mouse
Clonality
All clonalities for CXCR4 antibodies
Monoclonal
Conjugate
All conjugates for CXCR4 antibodies
This CXCR4 antibody is un-conjugated
Application
All applications for CXCR4 antibodies
Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
Purification
Affinity Chromatography
Clone
12G5
Isotype
IgG2a
Top Product
Discover our top product CXCR4 Primary Antibody
Alternatives
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Application Details
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Application Notes
CXCR4 antibody can be used in immunohistochemistry starting at 10 μg/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS, pH 7.2, 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze thaw cycles
Storage
4 °C
Storage Comment
Store CXCR4 antibody at 4 °C, Avoid Freezing
Target Details for CXCR4
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Target
CXCR4
(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
Alternative Name
CXCR4 (CXCR4 Products )
Synonyms
CD184 antibody, D2S201E antibody, FB22 antibody, HM89 antibody, HSY3RR antibody, LAP3 antibody, LCR1 antibody, LESTR antibody, NPY3R antibody, NPYR antibody, NPYRL antibody, NPYY3R antibody, WHIM antibody, Cmkar4 antibody, PB-CKR antibody, PBSF/SDF-1 antibody, Sdf1r antibody, CXC-R4-B antibody, CXCR-4-B antibody, cd184 antibody, cxcr4 antibody, fb22 antibody, hm89 antibody, hsy3rr antibody, lap3 antibody, lcr1 antibody, lestr antibody, npy3r antibody, npyr antibody, npyrl antibody, npyy3r antibody, xcxcr4 antibody, CXC-R4 antibody, CXCR-4 antibody, d2s201e antibody, whim antibody, CXC-R4-A antibody, CXCR-4-A antibody, xCXCR4 antibody, CXCR4 antibody, cb403 antibody, zgc:109863 antibody, cb824 antibody, C-X-C motif chemokine receptor 4 antibody, chemokine (C-X-C motif) receptor 4 antibody, C-X-C motif chemokine receptor 4 S homeolog antibody, C-X-C chemokine receptor type 4 antibody, C-X-C motif chemokine receptor 4 L homeolog antibody, chemokine (C-X-C motif), receptor 4b antibody, chemokine (C-X-C motif) receptor 4a antibody, CXCR4 antibody, Cxcr4 antibody, cxcr4.S antibody, cxcr4 antibody, LOC100049444 antibody, cxcr4.L antibody, cxcr4b antibody, cxcr4a antibody
Background
CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.
Gene ID
7852
UniProt
P61073
Pathways
Regulation of Cell Size , CXCR4-mediated Signaling Events
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